In Vitro Synergistic Efficacy of Various Antibiotic Combinations against Multi-drug-resistant Pseudomonas Aeruginosa Isolates Obtained from Patients in Intensive Care Units
نویسندگان
چکیده
Pseudomonas aeruginosa (P. aeruginosa) is a gram-negative opportunistic pathogen and a major cause of nosocomial infections. The pathogenicity of P. aeruginosa is multifactorial and associated with cell related alginates, pili and lipopolysaccharides as well as extracellular virulence factors such as proteases, haemolysins, toxins and pyocyanins. Its adaptability and high intrinsic antibiotic resistance enable it to survive in a wide range of other natural and artificial settings, including surfaces in Acta Medica Mediterranea, 2016, 32: 1041
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